Over
time, scientists and researchers have discovered that HCV’s viral RNA mutates.
It changes its shape constantly and evades the host’s immune system thereby
ensuring that it cannot be identified and eliminated by the host’s immune
system. The regions of the virus that codes for envelope proteins are the
regions that are most prone to mutation. This change of envelope proteins in
the mutated virus makes the virus unrecognizable by the body’s immune system,
and thus, it cannot be eliminated by the body’s immunity (Mandal, n. d.). It is
this changeability that thwarts the development of a very effective vaccine
against the virus.
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| (The Hepatitis C Virus, n. d.) |
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